Oprah Winfrey is set to close Harpo studio in Chicago this December where She has anchored her live talk show for more than 20years now. Announced by Oprah Winfrey and the Harpo studios on Tuesday. Oprah Winfrey sold the Harpo studio property last year in Chicago West Loop neighborhood to a developer for about $32 US million. And She concluded by saying the studio has truly been a blessing to her life. As She looks forward moving on to her studio in California.